Exosomes are nano-sized extracellular vesicles floating in our body fluids. Every cell releases these vesicles, which are known to play a role in intercellular communication. Especially, tumor cell-derived exosomes contain a lot of biomolecules (proteins, nucleic acids, and lipids) originated from their parent tumor cells, so that they can be employed as useful biomarkers for cancer. Our lab is now working on exosome detection and analysis studies using nanotechnology and several signal analysis methods for practical diagnosis of critical cancers such as lung cancer and leukemia.

-“Early-Stage Lung Cancer Diagnosis by Deep Learning-Based Spectroscopic Analysis of Circulating Exosomes”, ACS Nano (2020)
-“Correlation between Cancerous Exosomes and Protein Markers Based on Surface-Enhanced Raman Spectroscopy (SERS) and Principal Component Analysis (PCA)”, ACS Sensors (2018)
-“Exosome Classification by Pattern Analysis of Surface-enhanced Raman Spectroscopy Data for Lung Cancer Diagnosis”, Analytical Chemistry (2017)